Scientific SessionPediatric and Adolescent Treatment Concepts
Jonathan Friedberg
Christine Mauz-Körholz
08:00–08:20
Recent achievements and future goals in Pediatric and Young Adult HL: COG Perspective
Sharon Castellino
08:20–08:40
Recent achievements and future goals in Pediatric and Young Adult HL: EuroNET-PHL Perspective
Christine Mauz-Körholz
08:40–09:00
Appropriate endpoints for future trials in Pediatric and Young Adult HL, and opportunities for harmonization
Jamie Flerlage
Kara Kelly
09:00–09:10
EFFICACY and TOLERABILITY in DECOPDAC21 versus COPDAC28 in PEDIATRIC INTERMEDIATE and ADVANCED STAGE CLASSICAL HODGKIN LYMPHOMA: INTERIM RESULTS of the EURONET-PHL-C2 RANDOMIZED STUDY
Dieter Körholz
09:10–09:20
Progression-Free Survival (PFS) with Nivolumab-AVD is superior to Brentuximab Vedotin-AVD with 2-year follow-up of S1826 in Adolescent Advanced Stage (AS) Classic Hodgkin Lymphoma (cHL)
Sharon Castellino
09:20–09:30
Updated Results from the Phase 2 KEYNOTE-667 Study: Pembrolizumab (pembro) in Children and Young Adults With Low-Risk Classical Hodgkin Lymphoma (cHL) and Slow Early Response (SER) to Front-Line Chemotherapy (chemo)
Kara Kelly
10:00 – 11:30
Room: Großer Saal
Scientific SessionBiology & Microenvironment
Sirpa Leppä
Margaret Shipp
10:00–10:25
Pathogenesis of HL
Ralf Küppers
10:25–10:50
Multimodal characterization of cHL
Christian Steidl
10:50–11:00
Characterization of cancer-associated fibroblasts and their spatial architecture reveals heterogeneity and survival associations in classical Hodgkin lymphoma
Kristiina Karihtala
11:00–11:10
Circulating tumor DNA sequencing facilitates biological classification and individualized risk stratification in patients with Hodgkin lymphoma
Michel Heger
11:10–11:20
Distinct cell state ecosystems for nodular lymphocyte-predominant Hodgkin lymphoma
Michael Binkley
11:20–11:30
Multi-Dimensional Profiling Unveils Distinct Molecular Subtypes in Classic Hodgkin Lymphoma
Tomohiro Aoki
12:00 – 13:30
Room: Großer Saal
Satellite Symposium
(by MSD Sharp & Dohme GmbH)
New concepts for the treatment of
B-cell lymphomas
Peter Borchmann
12:00–12:30
B-cell lymphoma pathology – illustrated for non- pathologists
Wolfram Klapper
12:30–13:00
Classical Hodgkin Lymphoma - Development of immune checkpoint inhibition beyond PD-1 blockade
Peter Borchmann
13:00–13:30
Diffuse Large B-cell Lymphoma - The current and future role of ADC in the context of immunotherapies
Sascha Dietrich
14:00 – 15:30
Room: Großer Saal
Scientific SessionOlder Patients
Paul J. Bröckelmann
Andrew Evens
14:00–14:25
Implementing Frailty Assessment for Treatment Guidance in HL
Sarah Rutherford
14:25–14:50
Optimal Use of Targeted Agents to Address Unmet Need in Older HL
Graham Collins
14:50–15:00
A simplified frailty score predicts outcome in older patients with classical Hodgkin lymphoma treated with curative intent
Kjersti Lia
15:00–15:10
Characterisation of older Hodgkin Lymphoma patients using UK registry data from 1997-2023
Aisling Barrett
15:10–15:20
Feasibility and Efficacy of PET-guided BrECADD in Older Patients with Advanced-Stage classical Hodgkin Lymphoma: The Older Cohort of the International GHSG HD21 Trial
Justin Ferdinandus
15:20–15:30
Nivolumab-AVD improves 2-year progression-free and overall survival compared to Bv-AVD in older patients aged ≥60 years with advanced stage classical Hodgkin lymphoma (cHL) enrolled on SWOG S1826
Sarah Rutherford
16:00 – 17:30
Room: Großer Saal
Satellite Symposium
(by Takeda Pharmaceuticals USA, Inc.)
Real world impact: bridging between
clinical trial and real world experience in stages III &
IV 1L Hodgkin Lymphoma
John Radford
16:00–16:05
Welcome and introduction
16:05–16:15
Spotlight on ECHELON-1: 7-year survival data
John Radford
16:15–16:45
Real-world insights: frontline treatment of stages III & IV cHL
Immune-chemotherapy overcomes the need for individualization
Jonathan Friedberg
18:50–19:00
2-Year Follow-up of the S1826 Study Confirms Improved Progression-Free Survival with Nivolumab-AVD Compared to Brentuximab Vedotin-AVD in Advanced Stage Classic Hodgkin Lymphoma
Alex Herrera
19:00–19:10
Development and application of a validated MRD assay in Hodgkin Lymphoma
Julia Mattlener
19:10–19:20
EORTC-1537-COBRA: PHASE II STUDY OF VERY EARLY FDG-PET-RESPONSE ADAPTED TARGETED THERAPY FOR ADVANCED HODGKIN LYMPHOMA. PRIMARY ANALYSIS INCLUDING VALUE OF QUANTITATIVE PET ASSESSMENT AND TARC DYNAMICS
Martin Hutchings
19:20–19:30
Metabolic tumor volume after two cycles of chemotherapy in patients treated for advanced-stage Hodgkin Lymphoma: analysis of the German Hodgkin Study Group phase III HD18 and HD21 trials