Hodgkin lymphoma is one of the most frequently diagnosed malignancies in pregnancy. In the group of nine patients of one center with manifestation of Hodgkin lymphoma in pregnancy we demonstrate the management of diagnostic and therapeutic procedures. Seven patients were diagnosed in 20-30th week of pregnancy; one with progressive lymphadenopathy already before confirmation of pregnancy and one patient with the diagnosis in 7th week. Only in one case there was induced abortion, and in one case the corticotherapy was started in the third trimester, in the rest of patients (7) the therapy was started after the delivery. Although there are some publications about therapy with single vinblastin, respectively combination chemotherapy ABVD in the second half of pregnancy, our experiences are based on preferation of thorough observation in pregnancy and indication of specific chemotherapy after delivery.
This work was supported by grant awarded by AZV 16-29857A, Ministry of Health in Czech Republic and Research project P 27/2012 awarded by Charles University in Prague, 3rd Faculty of Medicine, Prague, Czech Republic